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Beilstein J. Org. Chem. 2021, 17, 494–503, doi:10.3762/bjoc.17.43
Graphical Abstract
Scheme 1: Synthesis of organocatalyst 5.
Figure 1: Structures of the screened organocatalysts.
Scheme 2: Proposed transition state for the SMA of 1-thionaphthol to trans-chalcones.
Figure 2: Comparison of the ee values of SMA in the presence of THF and DCM as solvent.